An experimental and theoretical study of lymphocyte cytotoxicity against tumor cells
Gorman, Arthur D.; Kurt, Robert A.
There are a number of existing mathematical models that attempt to describe the cellular interactions between the immune system and tumor cells. Most, however,
are too complicated to be solved analytically and are beyond the scope of use for the majority of investigators interested in immunotherapy. Consequently, we previously developed a simple mathematical model that could be solved analytically and established a web site to facilitate use among the community of investigators
wishing to utilize the model. Here we take the mathematical analysis of tumor immunity a step further by comparing it to the decay of radioisotopes. These two
unrelated processes are remarkably similar mathematically. Moreover, this new way of modeling the effector cell response to cancer is even simpler than the previous
mathematical model we generated, and thus provides a straightforward tool to examine effector cell/tumor cell interactions.
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